Seventy-five years down the line, FAO’s name, ambition and spirit remain: everything else has changed, and will change further. Born in 1945 amid the idealism of post-war reconstruction, the Food and Agriculture Organization of the United Nations sets out to increase farm output around the world and make famines a thing of the past. Over the subsequent 75 years, FAO’s outlook and body of work acquire new environmental and sustainability dimensions. By 2020, continued success requires strategic re-invention. As the COVID-19 pandemic exacerbates vulnerabilities linked to conflict and climate change, FAO is looking to advanced research partnerships, digitalization and wall-to-wall innovation to help end hunger and malnutrition. With ten years to go until the Sustainable Development Goals come due, the race is on for bold answers and dramatic solutions.