This publication sets out the Agenda ARCAL 2030, the title given to the Regional Strategic Profile for Latin America and the Caribbean for the period from 2022 to 2029. It will serve as a key programmatic reference for the formulation of regional technical cooperation projects. As with previous editions of the Regional Strategic Profile, the IAEA, the Regional Co-operation Agreement for the Promotion of Nuclear Science and Technology in Latin America and the Caribbean (ARCAL) and representatives of Member States collaborated closely on the drafting of this new strategic programming framework. The new framework aims to address those of the region’s priority needs and problems where nuclear technology can make an effective and tangible contribution.