This publication describes the general concept of using quantitative and qualitative information to be integrated in making safety related decisions. By following this approach, the balanced decision option could be selected in a systematic and traceable manner. The publication also provides practical insights on the selection of the various factors that could be included in the integrated risk informed decision making (IRIDM) process and provides suggestions on how the integration of the factors can be performed. Practical issues and challenges that need to be addressed in adopting an IRIDM approach are also discussed. Some examples of decision making are reviewed against the IRIDM framework to show how the process has been used or can be used.