This collection of essays explores the cultural significance of children’s reading by analyzing a series of Anglo-American case studies from the eighteenth century to the present. Marked by historical continuity and technological change, children’s reading proves to be a phenomenon with broad influence, one that shapes both the development of individual readers and wider social values. The essays in this volume capture such complexity by invoking the conception of “mediation” to approach children’s reading as a site of interaction among individual people, material texts, and institutional networks. Featuring a range of scholarly perspectives from the disciplines of literature, education, graphic design, and library and information science, this collection uncovers both the intricacies and wider stakes of children’s reading. The books, public programs, and archives that focus explicitly on children’s interests and needs are powerful arenas that give expression to the key ideological investments of a culture.