This book brings together a diverse range of scholars and practitioners working at the nexus of health literacy work in libraries. This engaging resource presents a practical and accessible guide to meet the needs of librarians, health literacy researchers, and information and service professionals seeking to address health literacy needs in their communities. Through chapters offering multiple perspectives on the topic, the book covers specific types of literacy, such as mental health literacy and health insurance literacy, as well as timely applications, such as health misinformation. Chapters in this compilation also feature health literacy and the following communities: LGBTQ+, Latinx, Black, and Immigrants, Refugees, and Migrants. The book is full of numerous examples, thoughtful advice, and discussions addressing the challenges of working with adolescents and young adults, older adults, and parent caregivers of children with rare diseases. Each chapter starts with “Key Messages'' synthesizing the main points and concludes with a proposed set of “Discussion Questions'' to inspire further reflection and to facilitate health literacy conversations. Overall, the up-to-date coverage of health literacy in various contexts explored throughout the book will be beneficial to a range of stakeholders interested in health literacy work.