In a surprising number of espionage cases sex has played a significant role—often only in the background—possibly as a reason why a particular individual has lived beyond his means and is in desperate need of cash. FBI agent Earl Pitts sold secrets to the Soviets to ease his financial burdens, which came from his habitually heavy use of male and female prostitutes. Yuri Nosenko collaborated with the CIA after having misappropriated KGB funds to entertain expensive women while on official duties in Geneva, and Aleksandr Ogorodnik of the Soviet foreign ministry was persuaded to become a spy by his pregnant Spanish lover, an agent recruited by the CIA.

In the realm of human behavior, sex can be the catalyst for risky or reckless conduct. The A to Z of Sexspionage explores this behavior through a chronology, an introduction, a bibliography, and hundreds of cross-referenced dictionary entries on the secret agencies, operations, and events. From Delilah's seduction of Samson in 1161 BC to State Department official Donald Keyser's conviction of passing secrets to Isabelle Cheng, a Taiwanese intelligence officer, in 2007, Nigel West recounts the history of sexspionage.